Diastereoselective allylation of planar chiral substituted ferrocenecarboxaldehyde: an efficient entry to chiral ferrocenyl ligands

作者：Li Hao; Cheng Hin Soon; Seow Ai Hua; Loh Teck Peng^*

来源：Tetrahedron Letters, 2007, 48(12): 2209-2211.

DOI：10.1016/j.tetlet.2007.01.065

• 2,2 '-disubstituted ferrocenecarboxaldehydes
• allylation
• chiral ferrocenyl complexes

2,2'-Disubstituted ferrocenecarboxaldehydes are subjected to zinc-mediated allylation to form homoallylic ferrocenyl alcohols. The effects of ortho-substituted functional groups on facial selectivities of planar chiral aldehydes were studied and it was found that the corresponding homoallylic alcohols were obtained as single diastereomers in excellent yields.

• 出版日期2007-3-19
• 单位南阳理工学院