A lotus root inspired implant system with fever responsive characteristics and 3D printing defined nano-antibiotic release patterns

作者:Ding, Xingwei; He, Xiaoyi; Xue, Chaowen; Wu, Changwen; Xie, Lin; Chen, Tingtao; Wei, Junchao; Cheng, Xigao; Wang, Xiaolei*
来源:RSC Advances, 2016, 6(80): 76785-76788.
DOI:10.1039/c6ra10652h

摘要

Lotus root imitated implant scaffolds with highly flexible drug release patterns were fabricated. Several critical release parameters could be conveniently prearranged through creating a precisely customized inner chamber via 3D printing. Furthermore, when postoperative infection caused hyperthermia, the inner drugs could be spontaneously released to inhibit the invasive pathogens.