摘要
The synthesis of functionalized azepenes and piperidines bearing an alpha-cycloheptenone or benzotropone derivative has been accomplished through direct reductive cross-coupling of alpha-bromo eneformamides or enecarbamates with highly versatile alpha-bromo benzotropone derivatives, under cobalt catalysis. The coupling products have been further elaborated to other synthetically useful aza-heterocyclic frameworks.
- 出版日期2015