Acute and Potentially Life-Threatening Tropical Diseases in Western Travelers-A GeoSentinel Multicenter Study, 1996-2011

作者：Jensenius Mogens^*; Han Pauline V; Schlagenhauf Patricia; Schwartz Eli; Parola Philippe; Castelli Francesco; von Sonnenburg Frank; Loutan Louis; Leder Karin; Freedman David O

来源：The American Journal of Tropical Medicine and Hygiene, 2013, 88(2): 397-404.

DOI：10.4269/ajtmh.12-0551

We performed a descriptive analysis of acute and potentially life-threatening tropical diseases among 82,825 ill western travelers reported to GeoSentinel from June of 1996 to August of 2011. We identified 3,655 patients (4.4%) with a total of 3,666 diagnoses representing 13 diseases, including falciparum malaria (76.9%), enteric fever (18.1%), and leptospirosis (2.4%). Ninety-one percent of the patients had fever; the median time from travel to presentation was 16 days. Thirteen (0.4%) patients died: 10 with falciparum malaria, 2 with melioidosis, and 1 with severe dengue. Falciparum malaria was mainly acquired in West Africa, and enteric fever was largely contracted on the Indian subcontinent; leptospirosis, scrub typhus, and murine typhus were principally acquired in Southeast Asia. Western physicians seeing febrile and recently returned travelers from the tropics need to consider a wide profile of potentially life-threatening tropical illnesses, with a specific focus on the most likely diseases described in our large case series.

• 出版日期2013-2