Neuromyelitis optica-IgG(+) optic neuritis associated with celiac disease and dysgammaglobulinemia: A role for tacrolimus?

作者：Meyts Isabelle^*; Jansen Katrien; Renard Marleen; Bossuyt Xavier; Roelens Filip; Regal Luc; Lagae Lieven; Buyse Gunnar

来源：European Journal of Paediatric Neurology, 2011, 15(3): 265-267.

DOI：10.1016/j.ejpn.2010.09.005

• Neuromyelitis optica
• Anti-aquaporine 4
• Celiac disease
• Tacrolimus

We present a pediatric case of recurrent optic neuritis, celiac disease, partial IgA and IgG3 deficiency in the context of anti-aquaporin-4 auto-immunity and familial IgA deficiency with celiac disease. Treatment with tacrolimus was successful in preventing disease relapses. This case stresses the relevance of central nervous system anti-aquaporin-4 auto-immunity in a broader context of immune dysregulation and neuro-immunology.

• 出版日期2011-5