Muscle, Health and Costs: A Glance at their Relationship

作者：Mijnarends D M; Luiking Y C; Halfens R J G; Evers S M A A; Lenaerts E L A; Verlaan S; Wallace M; Schols J M G A^*; Meijers J M M

来源：Journal of Nutrition Health & Aging, 2018, 22(7): 766-773.

DOI：10.1007/s12603-018-1058-9

• Muscle
• activities of daily living
• quality of life
• health care costs

To assess the association between muscle parameters (mass, strength, physical performance) and activities of daily living (ADL), quality of life (QoL), and health care costs.
Cross-sectional Maastricht Sarcopenia Study (MaSS).
Community-dwelling, assisted-living, residential living facility.
227 adults aged 65 and older.
Muscle mass, hand grip strength and physical performance were assessed by bio-electrical impedance, JAMAR dynamometer and the Short Physical Performance Battery, respectively. Health outcomes were measured by the Groningen Activity Restriction Scale (disability in ADL) and the EQ-5D-5L (QoL). Health care costs were calculated based on health care use in the past three months.
Muscle strength and physical performance showed a strong correlation with ADL, QoL, and health care costs (P <.01); for muscle mass no significant correlations were observed. Regression analyses showed that higher gait speed (OR 0.06, 95%CI 0.01-0.55) was associated with a lower probability of ADL disability. Furthermore, slower chair stand (OR 1.23, 95%CI 1.08-1.42), and more comorbidities (OR 1.58, 95%CI 1.23-2.02) were explanatory factors for higher ADL disability. Explanatory factors for QoL and costs were: more disability in ADL (OR 1.26, 95%CI 1.12-1.41 for QoL; B = 0.09, P <.01 for costs) and more comorbidities (OR 1.44, 95%CI 1.14-1.82 for QoL; B = 0.35, P <.01 for costs).
Lower gait speed and chair stand were potential drivers of disability in ADL. Disability in ADL and comorbidities were associated with QoL and health care costs in community-dwelling older adults. Improving physical performance may be a valuable target for future intervention and research to impact health burden and costs.

• 出版日期2018-7