A simple method for the conversion of propargyl alcohols to symmetrical 1,5-diynes using low valent titanium reagents

作者：Karunakar Galla V; Periasamy Mariappan^*

来源：Tetrahedron Letters, 2006, 47(21): 3549-3552.

DOI：10.1016/j.tetlet.2006.03.097

• symmetrical 1,5-diynes
• low valent titanium species
• propargyl alcohols

Reaction of propargyl alcohols with low valent titanium species, prepared using the TiCl4/Et3N and TiCl4/Zn reagent systems, gives the corresponding symmetrical 1,5-diynes in 56-74% yields.

• 出版日期2006-5-22