Acceptability of meningococcal serogroup B vaccine among parents and health care workers in Italy: A survey

作者：Mameli Chiara; Faccini Marino; Mazzali Cristina; Picca Marina; Colella Giacomo; Duca Pier Giorgio; Zuccotti Gian Vincenzo^*

来源：Human Vaccines & Immunotherapeutics, 2014, 10(10): 3004-3010.

DOI：10.4161/21645515.2014.971602

• healthcare providers
• meningococcal B
• parents
• survey
• vaccine
• CI
• confidence interval
• HCWs
• health care workers
• MenB
• meningococcal serogroup B
• MenC
• Meningococcal serogroup C
• OR
• odds ratio

A new meningococcal serogroup B vaccine (4CMenB) has recently been licensed. This study assessed the acceptability of 4CMenB vaccine among parents and healthcare workers (HCWs). From May to July 2013 in Milan, Italy, self-administered questionnaires were distributed to 2050 parents of infants presenting at immunization clinics for the mandatory hexavalent vaccination and submitted to 350 HCWs involved in immunization practices.1842 parents (89.1%) responded to the survey; 64.4% of parents wanted their child to receive the 4CMenB vaccine and 5.1% would not vaccinate their children. Multivariate analysis showed that recognition of the severity of meningitis [a life threatening vs a mild or unthreatening disease (Odds ratio (OR): 2.3; confidence interval (CI): 1.4-3.6], awareness of vaccination as a beneficial preventive measure (very beneficial vs not beneficial OR=6.4; CI 3.0-13.7) and knowledge of the Meningococcal C vaccine (OR=1.4; CI 1.1-1.8) were strongly associated to willingness to receive 4CMenB vaccine. On the contrary, level of education was associated with refusal of immunization (university vs education level lower than middle school OR=0.68; CI 0.47-0.97). Among the parents who were willing to immunize their children, 66.9% would agree with three injections to be administered during the same visit. A total of 291 HCWs (83.1%) agreed to participate in the survey; 73% considered 4CMenB vaccine a priority in infants' immunization schedule; 26.8% of HCWs suggested the concomitant administration with routine infant immunization.Parental and HCWs acceptability of 4CMenB vaccine was high. Increasing knowledge about meningitis and vaccine prevention might further increase the acceptability of this vaccine.

• 出版日期2014-10