科研之友
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摘要
The synthesis of a series of aryl 5,5-spiroketals containing a 1,1'-spirobi(3H,3'H)isobenzofuran ring system is reported. The key step involves addition of an aryllithium derived from a protected bromobenzyl alcohol to a phthalide; this is followed by deprotection of the benzyl alcohol and acid-catalysed cyclisation.
- 出版日期2007-3-1
