An antibiotic stewardship program in a French teaching hospital

作者：Mondain V; Lieutier F; Dumas S; Gaudart A; Fosse T; Roger P M; Bernard E; Farhad R; Pulcini C^*

来源：Medecine et Maladies Infectieuses, 2013, 43(1): 17-21.

DOI：10.1016/j.medmal.2012.10.006

• Antibiotic stewardship
• Antibiotic management team
• DDD
• Infectious diseases specialist

Objectives. - An antibiotic stewardship program was implemented in our teaching hospital in 1999, and strengthened in 2005. We report its organization and impact on antibiotic use. %26lt;br%26gt;Methods. - This observational study was conducted during a 10-year period (2002-2011). %26lt;br%26gt;Results. - Many interventions were implemented: Infectious Diseases Specialists (IDS) led systematic ward rounds in several departments (1999); nominative antibiotic order form (2005); documentation of IDS advice in the patient%26apos;s electronic medical record (2007); IDS advice triggered by the pharmacist (formulary restriction, 2007) or because of positive blood cultures (2009); automated weekly extraction of advice given into a database (2011). Seven thousand two hundred and five pieces of advice were recorded between 2007 and 2011: 63% following physician request, 26% triggered by the pharmacist and 9% because of positive blood cultures. Advice was provided by IDS in 95% of cases (63% by phone). The number of antibiotic prescriptions remained stable since 2005 at around 400 defined daily doses (DDD)/1000 patient-days. Documenting, sharing, and choice of action were improved due to the database. %26lt;br%26gt;Conclusions. - Our antibiotic stewardship program is well accepted by physicians and allows controlling antibiotic use in our hospital.

• 出版日期2013-1