Asymmetric reduction of ketimines with trichlorosilane employing an imidazole derived organocatalyst

作者:Gautier Francois Moana; Jones Simon*; Martin Stephen J
来源:Organic and Biomolecular Chemistry, 2009, 7(2): 229-231.
DOI:10.1039/b816051a

摘要

Organocatalysts for the asymmetric reduction of ketimines are presented that function well at low catalyst loadings providing chiral amines in good yield and enantioselectivity, the latter appearing to be independent of the ketimine substrate geometry.

  • 出版日期2009