科研之友
微信
新浪微博
Facebook
分享链接
摘要
Experimental investigations have shown that the pre-Botzinger complex (pre-BotC) within the mammalian brainstem generates the inspiratory phase of respiratory rhythm. Based on a single-compartment model of a pre-BotC inspiratory neuron, we, in this paper, use semi-analytical, numerical as well as fast-slow dynamical methods to investigate the effects of sodium conductance (gNa) and potassium conductance (gK) on the firing activities of pre-BotC and try to reveal the dynamical mechanisms behind them. We show how gNa and gK affect the bifurcations of the fast-subsystem and how the the firing patterns of pre-BotC transit according to the bifurcations.
