Neonatal development and teratogenic potential of Wistar rats offspring in the study of reproductive toxicity of two commercial phytotherapic preparations with soy Glycine max (L.) Merr

作者：Hollenbach C B^*; Bortolini C E; Batista J M; Hollenbach E B; Schuch T L; Pacheco M H; Mello F B; Mello J R

来源：Arquivo Brasileiro de Medicina Veterinaria e Zootecnia, 2010, 62(4): 845-852.

• rat
• soy
• phytotherapic
• reproductive toxicology

The effect of two commercial phytotherapic preparations containing soy was evaluated on the general and sexual development of Wistar rats offspring and on the teratogenic potential during a reproductive toxicity study. For this, the offspring development characteristics were daily observed, and the behavior in open field was studied. To assess the teratogenic potential, diaphanization of the fetuses removed by caesarean section was done. It was concluded that the treatment of the parents did not compromise the development of their progeny and also did not determine the teratogenic effects in the fetuses.

• 出版日期2010-8