A stereoselective synthesis of ( )-physoperuvine using a tandem aza-Claisen rearrangement and ring closing metathesis reaction

作者：Zaed Ahmed M; Swift Michael D; Sutherland Andrew^*

来源：Organic and Biomolecular Chemistry, 2009, 7(13): 2678-2680.

DOI：10.1039/b907341h

A stereoselective synthesis of ( )-physoperuvine, a tropane alkaloid from Physalis peruviana Linne has been developed using a one-pot tandem aza-Claisen rearrangement and ring closing metathesis reaction to form the key amino-substituted cycloheptene ring.

• 出版日期2009