A new flavonoid from Sophora flavescens Ait

作者:Huang, Rong; Liu, Yi; Zhao, Lin-Lin; Chen, Xi-xin; Wang, Feng; Cai, Wei; Chen, Lei*
来源:Natural Product Research, 2017, 31(19): 2228-2232.
DOI:10.1080/14786419.2017.1297992

摘要

A new flavonoid, 8-(3-hydroxymethyl-2-butenyl)-5,7,2', 4'-tetrahydroxy-flavanone (1), along with seven known compounds, (2R)-3 alpha, 7,4'-Trihydroxy 5-methoxy-8-prenylflavanone (2), (2R)-3 beta, 7,4'-Trihydroxy-5-methoxy-8- prenylflavanone (3), 3,7-dihydroxycoumarin (4), Shandougenines B (5), Specionin (6), Kushenol N (7) and Kushenol I (8) were isolated from the roots of Sophora flavescens. Among them, Compound 5 was isolated from Leguminous plants, and compounds 4 and 6 were isolated from Sophora flavescens for the first time. Their structures were elucidated by the aid of NMR, HRMS, HMBC and CD spectroscopic methods.