Postnatal Infections and Immunology Affecting Chronic Lung Disease of Prematurity

作者：Pryhuber Gloria S

来源：Clinics in Perinatology, 2015, 42(4): 697-+.

DOI：10.1016/j.clp.2015.08.002

• Prematurity
• Neonatal immunology
• Neonatal infection
• Virus
• Lymphocytes
• Bronchopulmonary dysplasia
• Chronic lung disease of prematurity
• Preterm

Premature infants suffer significant respiratory morbidity during infancy with long-term negative consequences on health, quality of life, and health care costs. Enhanced susceptibility to a variety of infections and inflammation play a large role in early and prolonged lung disease following premature birth, although the mechanisms of susceptibility and immune dysregulation are active areas of research. This article reviews aspects of host-pathogen interactions and immune responses that are altered by preterm birth and that impact chronic respiratory morbidity in these children.

• 出版日期2015-12