A new xanthone from the fungus Apiospora montagnei

作者：Arthan Supakorn; Tantapakul Cholpisut; Kanokmedhakul Kwanjai^*; Soytong Kasem; Kanokmedhakul Somdej

来源：Natural Product Research, 2017, 31(15): 1766-1771.

DOI：10.1080/14786419.2017.1290622

• Apiospora montagnei
• xanthone
• cytotoxicity

A new xanthone derivative, methyl 8-hydroxy-3-hydroxymethylxanthone-1-carboxylate (1), and seven known compounds, 8-hydroxy-3-methylxanthone-1-carboxylate (2), methyl 8-hydroxy-6-methylxanthone-1-carboxylate (3), ergosterol (4), cyathisterone (5), ergosta-4,6,8(14),22-tetraen-3-one (6), calvasterone (7) and 2-hexyl-3-methylmaleic anhydride (8) were first isolated from the fungus Apiospora montagnei. Their structures were elucidated on the basis of spectroscopic analysis (UV, IR, MS, 1D, and 2D NMR). Compounds 5 and 6 showed weak to very weak cytotoxicity against cancer cell lines, NCI-H187 and KB.
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• 出版日期2017