A Case of Fasciola hepatica Infection Mimicking Cholangiocarcinoma and ITS-1 Sequencing of the Worm

作者:Kang Bong Kyun; Jung Bong Kwang; Lee Yoon Suk; Hwang In Kyeom; Lim Hyemi; Cho Jaeeun; Hwang Jin Hyeok*; Chai Jong Yil
来源:Korean Journal of Parasitology, 2014, 52(2): 193-196.
DOI:10.3347/kjp.2014.52.2.193

摘要

Fascioliasis is a zoonotic infection caused by Fasciola hepatica or Fasciola gigantica. We report an 87-year-old Korean male patient with postprandial abdominal pain and discomfort due to F hepatica infection who was diagnosed and managed by endoscopic retrograde cholangiopancreatography (ERCP) with extraction of 2 worms. At his first visit to the hospital, a gallbladder stone was suspected. CT and magnetic retrograde cholangiopancreatography (MRCP) showed an intraductal mass in the common bile duct (CBD) without proximal duct dilatation. Based on radiological findings, the presumed diagnosis was intraductal cholangiocarcinoma. However, in ERCP which was performed for biliary decompression and tissue diagnosis, movable materials were detected in the CBD. Using a basket, 2 living leaf-like parasites were removed. The worms were morphologically compatible with F hepatica. To rule out the possibility of the worms to be another morphologically close species, in particular F gigantica, 1 specimen was processed for genetic analysis of its ITS-1 region. The results showed that the present worms were genetically identical (100%) with F hepatica but different from F gigantica.

  • 出版日期2014-4