Direct electrochemistry of cytochrome c on a silica sol-gel film modified electrode

作者：Xu Jun Sheng; Zhao Guang Chao^*

来源：Electroanalysis, 2008, 20(11): 1200-1203.

DOI：10.1002/elan.200704164

• silica sol-gel
• cytochrome c
• direct electrochemistry
• biosensor

Dilute silica sol-gel was simply dropped on the surface of a basal plane graphite electrode (BPGE) to form a silica sol-gel film modified electrode. Direct electrochemical response of cytochrome c (Cyt c) on the modified electrode was observed by cyclic voltammetry (CV). The results suggested that Cyt c could be tightly adsorbed on the surface of the silica sol-gel film modified electrode. A couple of well-defined and nearly reversible redox peaks can be observed in a phosphate buffer solution (pH 7.0), which anodic and cathodic peak potentials were at -0.243 and -0.306 V (vs. Ag/AgCl), respectively. Cyt c adsorbed on the surface of silica sol-gel film shows a remarkable electrocatalytic activity for the reduction of oxygen. Based on these, a third-generation biosensor could be constructed to detect the concentration of oxygen in aqueous solution.

• 出版日期2008-6
• 单位安徽师范大学