Distal pancreatectomy. Radical or spleen-preserving?

作者：Chromik A M; Janot M; Suelberg D; Seelig M H; Uhl W^*

来源：Chirurg, 2008, 79(12): 1123-1133.

DOI：10.1007/s00104-008-1573-z

• Pancreatic tumor
• Chronic pancreatitis
• Overwhelming postsplenectomy infection
• Pancreatic fistula
• Pancreatic surgery

During recent years, spleen-preserving distal pancreatectomy (SPDP) has broadened the operative spectrum in pancreatic surgery. The rationale for spleen-preserving procedures comprises prevention of overwhelming postsplenectomy infection syndrome (OPSI) and possibly an advantage regarding reduced carcinogenesis. Although there are no prospective randomized trials, SPDP and distal pancreatectomy with splenectomy (DPSx) seem to be equivalent in terms of blood loss, operative time, mortality and frequency of reoperation. Concerning pancreatic fistulas and other major surgical complications, current data from the literature are conflicting. Long-term effects of SPDP, such as development of gastric varices due to portal hypertension, are still insufficiently investigated. However, SPDP should always be considered in patients with benign tumors of the pancreatic tail and chronic pancreatitis. Spleen-preserving distal pancreatectomy can also be combined with resection of the splenic vessels (DPSx-SVx) if the blood supply of the spleen via the small gastric vessels and the gastro-epoploic arcade is sufficient. In the presence of malignant tumors, DPSx is necessary for oncological reasons.

• 出版日期2008-12