Ultrasound measurements of brain tissue pulsatility correlate with the volume of MRI white-matter hyperintensity

作者：Ternifi Redouane^*; Cazals Xavier; Desmidt Thomas; Andersson Frederic; Camus Vincent; Cottier Jean Philippe; Patat Frederic; Remenieras Jean Pierre

来源：Journal of Cerebral Blood Flow and Metabolism, 2014, 34(6): 942-944.

DOI：10.1038/jcbfm.2014.58

• brain imaging
• cerebral blood flow measurement
• leukoaraiosis
• pulsatility
• ultrasound tissue displacement
• white-matter disease

White-matter hyperintensity (WMH) is frequently seen in magnetic resonance imaging (MRI), but the complete physiopathology of WMH remains to be elucidated. In this study, we sought to determine whether there is an association between the maximum brain tissue displacement (maxBTD), as assessed by ultrasound, and the WMH, as observed by MRI. Nine healthy women aged 60 to 85 years underwent ultrasound and MRI assessments. We found a significant negative correlation between maxBTD and WMH (p= -0.86, P<0.001), suggesting a link between cerebral hypoperfusion and WMH.

• 出版日期2014-6