A New Sensitive Fluorescent H2S Probe Based on Cu2+ Complex

作者:Huang Bin; Chen Yun-Cong; Guo Zi-Jian; He Wei-Jiang*
来源:Chinese Journal of Inorganic Chemistry, 2013, 29(11): 2283-2288.
DOI:10.3969/j.issn.1001-4861.2013.00.347

摘要

As the third gasotransmitter after NO and CO, hydrogen sulfide plays essential biological roles in living systems, and developing sensitive fluorescent probe for the rapid tracking of endogenous H2S is attracting much attention. A new H2S fluorescent probe was constructed in this study based on a copper complex formed by a new NBD fluorescent ligand, in which a Cu2+ chelator was incorporated. This probe displays very weak emission owing to the emission quenching effect of Cu2+, and it is able to sense H2S by exhibiting distinct emission enhancement upon H2S addition. The S2--induced Cu2+ removal from this complex was proposed as the sensing mechanism of this Cu2+ complex-based probe. Besides the quick response, the high sensing selectivity over other anion of this probe has also been confirmed, and its detection limit was estimated to be similar to 0.2 mu mol.L-1 and the linear range is 1 similar to 20 mu mol.L-1.

  • 出版日期2013-11-10
  • 单位南京大学; 现代配位化学国家重点实验室

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