Direct and convenient method of regioselective benzylation of methyl alpha-D-glucopyranoside

作者：Li Xiaoliu^*; Li Zhiwei; Zhang Pingzhu; Chen Hua; Ikegami Shiro

来源：Synthetic Communications, 2007, 37(13): 2195-2202.

DOI：10.1080/00397910701397326

• benzylation
• glucopyranoside
• regioselectivity
• selective protection

A facile and convenient method for the direct preparation of methyl 2,3,6-tri-O-benzyl-alpha-D-glucopyranoside (2) by the regioselective benzylation of methyl alpha-D-glucopyranoside (1) with benzyl bromide in the presence of mild bases K2CO3 and KOH (1:1) without solvents is reported.

• 出版日期2007
• 单位河北大学