A one pot three-step process for the synthesis of an array of arylated benzimidazoribosyl nucleosides

作者:Haluszczak Jolanta; Macdonald Simon J F; Migaud Marie E*
来源:Organic and Biomolecular Chemistry, 2011, 9(8): 2821-2831.
DOI:10.1039/c0ob00866d

摘要

A three-step one pot reaction/purification protocol was developed to facilitate rapid access to benzimidazole-based nucleosides, for which benzoylated benzimidazoribosyl nucleosides incorporating boronic esters were key reaction intermediates.

  • 出版日期2011