科研之友
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摘要
Hand-foot-mouth (HEM) disease is primarily a disease of children, although it can be seen in immunocompromised adults. We describe a case of HEM disease in a 35-year-old immunocompetent male. He presented with multiple, 1 similar to 2 mm sized, erythematous vesicular papules on both hands and feet. Histopathological findings of a skin biopsy showed superficial perivascular lymphocytic infiltration, focal keratinocyte necrosis, and reticular degeneration. Because delayed diagnosis can cause spread of the disease to children, dermatologists should be aware that HFM disease can occur in adults with intact immune systems. (Ann Dermatol 22(2) 216 similar to 218, 2010)
- 出版日期2010-5
