Microencapsulation of indocyanine green for potential applications in image-guided drug delivery

作者：Zhu, Zhiqiang; Si, Ting^*; Xu, Ronald X.

来源：Lab on a Chip, 2015, 15(3): 646-649.

DOI：10.1039/c4lc01032a

• DOUBLE EMULSION
• LIPID VESICLES
• PHOSPHOLIPID-VESICLES
• THERAPY
• ICG
• NANOPARTICLES
• ENCAPSULATION
• LIPOSOMES
• RELEASE
• SYSTEMS

We present a novel process to encapsulate indocyanine green (ICG) in liposomal droplets at high concentration for potential applications in image-guided drug delivery. The microencapsulation process follows two consecutive steps of droplet formation by liquid-driven coaxial flow focusing (LDCFF) and solvent removal by oil phase dewetting. These biocompatible lipid vesicles may have important applications in drug delivery and fluorescence imaging.

• 出版日期2015
• 单位中国科学技术大学