Health-related Quality of Life in Pediatric Patients With Long-standing Pancreatitis

作者：Pohl John F^*; Limbers Christine A; Kay Marie; Harman Annette; Rollins Michael; Varni James W

来源：Journal of Pediatric Gastroenterology and Nutrition, 2012, 54(5): 657-663.

DOI：10.1097/MPG.0b013e3182407c4f

• health-related quality of life
• pancreatitis
• pediatrics
• PedsQL

Objectives: There are limited data on health-related quality of life (HRQOL) in pediatric patients with long-standing pancreatitis (including acute relapsing and chronic pancreatitis) using age-appropriate measurement instruments. %26lt;br%26gt;Methods: We evaluated HRQOL in children with long-standing pancreatitis using the PedsQL 4.0 Generic Core Scales by patient self-report as well as parent proxy report. Additionally, patient self-reports and parent proxy reports were completed for the PedsQL Multidimensional Fatigue Scale. %26lt;br%26gt;Results: Across all of the dimensions, significantly impaired HRQOL and higher fatigue were noted for both pediatric patient self-report and parent proxy report in comparison with the matched healthy children samples. Higher fatigue was associated with lower HRQOL. There was moderate to good agreement between patient self-reports and parent proxy reports. %26lt;br%26gt;Conclusions: Given the impaired HRQOL and fatigue documented in the present study, future studies are needed to determine whether specific factors can modify HRQOL and fatigue in this patient population.

• 出版日期2012-5