Al(OTf)(3) as a highly efficient catalyst for the rapid acetylation of alcohols, phenols and thiophenols under solvent-free conditions

作者：Kamal Ahmed^*; Khan M Naseer A; Reddy K Srinivasa; Srikanth Y V V; Krishnaji T

来源：Tetrahedron Letters, 2007, 48(22): 3813-3818.

DOI：10.1016/j.tetlet.2007.03.162

Aluminium triflate (0.01-0.1 mol %) was found to be an efficient catalyst for the acylation of alcohols, phenols, thiols and sugars with acetic anhydride in high yields under solvent-free conditions in a short reaction time at room temperature. Racemization of optically active alcohols and epimerization of sugars were not observed. The acylation efficacy of various acyl donors was also investigated.

• 出版日期2007-5-28