A new 12,17-cyclo-labdane diterpenoid from the twigs of Dacrycarpus imbricatus

作者:Yang, Zuofa; Wang, Qiuxiang; Peng, Wei; Zhan, Rui; Chen, Yegao*
来源:Natural Product Research, 2018, 32(14): 1669-1675.
DOI:10.1080/14786419.2017.1395434

摘要

A new 12,17-cyclo-labdane diterpenoid, podoimbricatin C (1), along with 15 known compounds was isolated from the twigs of Dacrycarpus imbricatus. Their structures were elucidated by means of extensive spectroscopic analysis. Compound 1 is the second example of the unusual 12,17-cyclo-labdane diterpenoids. It showed no inhibitory effects against five human tumour lines (HL-60, SMMC-7721, A-549, MCF-7 and SW-480). [GRAPHICS] .