科研之友
微信
新浪微博
Facebook
分享链接
摘要
Chromene and spirocyclic 2-oxindole derivatives were readily synthesized in good yields via a one-pot three-component reaction involving Knoevenagel condensation of aromatic aldehyde or isatin with an active methylene reagent then the intermediate was reacted with another different active methylene reagent via a DABCO-catalysed Michael addition to yield the main products. Some advantages of this protocol are good yields, use of available catalysts, simple workup procedure and short reaction times. All synthesized products were characterized by FT-IR, H-1- and C-13-NMR spectroscopy.
- 出版日期2013-8
