Acute post-exercise change in blood pressure and exercise training response in patients with coronary artery disease

作者：Kiviniemi Antti M; Hautala Arto J; Karjalainen Jaana J; Piira Olli Pekka; Lepojarvi Samuli; Ukkola Olavi; Huikuri Heikki V; Tulppo Mikko P^*

来源：Frontiers in Physiology, 2015, 5: 526.

DOI：10.3389/fphys.2014.00526

• ischemic heart disease
• hypertension
• arterial pressure
• training adaptation
• acute exercise
• exercise testing
• autonomic function

We tested the hypothesis that acute post-exercise change in blood pressure (BP) may predict exercise training responses in BP in patients with coronary artery disease (CAD). Patients with CAD (n = 116, age 62 +/- 5 years, 85 men) underwent BP assessments at rest and during 10-min recovery following a symptom-limited exercise test before and after the 6-month training intervention (one strength and 3-4 aerobic moderate-intensity exercises weekly). Post-exercise change in systolic BP (SBP) was calculated by subtracting resting SBP from lowest post-exercise SBP. The training-induced change in resting SBP was -2 +/- 13 mmHg (p = 0.064), ranging from -42 to 35 mmHg. Larger post-exercise decrease in SBP and baseline resting SBP predicted a larger training-induced decrement in SBP (beta = 0.46 and beta = -0.44, respectively, p < 0.001 for both). Acute post-exercise decrease in SBP provided additive value to baseline resting SBP in the prediction of training-induced change in resting SBP (R-2 from 0.20 to 0.26, p = 0.002). After further adjustments for other potential confounders (sex, age, baseline body mass index, realized training load), post-exercise decrease in SBP still predicted the training response in resting SBP (beta = 0.26, p = 0.015). Acute post-exercise change in SBP was associated with training-induced change in resting SBP in patients with CAD, providing significant predictive information beyond baseline resting SBP.

• 出版日期2015-1-12