Microwave Irradiation as an Effective Means of Synthesizing Unsubstituted N-Linked 1,2,3-Triazoles from Vinyl Acetate and Azides

作者：Hansen Signe Grann; Jensen Henrik Helligso^*

来源：Synlett, 2009, 2009(20): 3275-3278.

DOI：10.1055/s-0029-1218366

• 1,2,3-triazole
• vinyl acetate
• microwave irradiation
• one-pot reaction
• 1,3-dipolar cycloaddition

N-Linked 1,2,3-triazoles have been prepared by a reaction of azides with vinyl acetate under microwave irradiation. Additionally, a microwave-assisted, two-step, one-pot procedure from halides involving azide substitution in diethyl ether, followed by reaction with vinyl acetate, has effectively been employed.

• 出版日期2009-12