Parenchymal density changes in acute pulmonary embolism: Can quantitative CT be a diagnostic tool? A preliminary study

作者：Duman Ikram Eda; Cimsit Canan^*; Yildizeli Sehnaz Olgun; Cimsit Nuri Cagatay

来源：Clinical Imaging, 2017, 41: 157-163.

DOI：10.1016/j.clinimag.2016.11.005

• Pulmonary embolism
• Quantitative Cr
• Density mapping
• CIPA

Purpose: Determine the ability of quantitative CT (QCT) in defining parenchymal density changes in acute pulmonary embolism (PE).
Material & methods: Mean lung density (MLD) and percentage distribution values (PDV) were calculated in 34 patients suspected of PE using software application based on computerized volumetric anatomical segmentation.
Results: Total, left, and right MLD differed significantly between emboli positive(n = 23) and negative(n = 11) groups(p < 0.006, p < 0.009, p < 0.014). PDVs differed between groups (p < 0.05) except for LUZ and RLZ. When PE was present in lobe &/segment branches, PDVs were significantly lower except RUZ.
Conclusion: QCT is a promising application for defining parenchymal density changes in PE revealing potential functional impact of emboli. This preliminary study suggests QCT could provide added value to CTPA in peripheral PE.

• 出版日期2017-2