摘要

Hydrogels offer attractive properties, Such as unique softness, biocompatibility and biomimetic performance. Electrodes modified with hydrogels would decrease peak-to-peak noise signals and overcome the limitation of present biosensors in biocompatibility and tissue-to-electrode interaction. In this paper, recent advances on hydrogel-modified electrodes are reviewed. Current preparation methods of hydrogel-modified electrodes are summarized, including dip-coating, covalent binding, electrochemistry and layer-by-layer self-assembly. Furthermore, an overview is given for the applications of hydrogels in neural electrodes, enzyme-modified electrodes, redox protein-modified electrodes, pH sensors and other sensors. Finally, the challenges and promising developments of hydrogel-modified electrodes are prospected.