Antioxidative Properties of Silymarin, 7-aminoflavone, Neohesperidin Dihydrochalcone and Trihydroxyethylenorutin Studied by the Electrochemical Methods

作者：Masek Anna^*; Chrzescijanska Ewa; Zaborski Marian

来源：International Journal of Electrochemical Science, 2014, 9(12): 7875-7889.

DOI：10.1016/s1452-3981(23)11012-1

• flavonoids
• electrooxidation
• platinum electrode
• FTIR spectroscopy

The electrooxidation of flavonoids has been investigated in non-aqueous solution at a platinum electrode. The process of oxidation and its kinetics has been investigated using cyclic voltammetry (CV) and differential pulse voltammetry (DPV). The electrochemical oxidation of flavonoids is an irreversible reaction at a platinum electrode. For neohesperidin dihydrochalcone, silymarin, 7-aminoflavone and trihydroxyethylenorutin, the first step in the electrooxidation is the exchange of one electron during the oxidation of the hydroxyl group in ring B. The hydroxyl groups in ring A are likely oxidised in a subsequent step. Neohesperidin dihydrochalcone oxidation was the easiest, and trihydroxyethylenorutin was the hardest, which was confirmed by the half-wave potential (E-1/2) of the first electrode step in the electrooxidation of the flavonoids. Structural investigations of the flavonoids were conducted using FTIR spectroscopy. The voltammetric potentials were found to correlate well with computed highest occupied molecular orbital (HOMO) energies.

• 出版日期2014-12