A dihydrochalcone derivative and further steroidal saponins from Sansevieria trifasciata Prain

作者:Tchegnitegni Billy T; Teponno Remy B; Jenett Siems Kristina; Melzig Matthias F; Miyamoto Tomofumi; Tapondjou Leon A*
来源:Zeitschrift fur Naturforschung Section C-A Journal of Biosciences, 2017, 72(11-12): 477-482.
DOI:10.1515/znc-2017-0027

摘要

Phytochemical investigation of the aerial parts of Sansevieria trifasciata, one of the most common Dracaenaceae plants, has resulted in the isolation of a new dihydrochalcone derivative named trifasciatine C (1), four previously unreported steroidal saponins as two pairs of inseparable regioisomers: trifasciatosides K/L (2/3), M/N (4/5), together with the known 1,2-(dipalmitoyl)-3O-beta-D-galactopyranosylglycerol (6), aconitic acid (7), and 1-methyl aconitic acid (8). Their structures were elucidated mainly by extensive spectroscopic analysis (1D and 2D nuclear magnetic resonance) and high-resolution electronspray ionization-mass spectrometry, as well as chemical methods and comparison of their spectral data with those of related compounds. Compounds 2/3 and 4/5 were evaluated for their antiproliferative activity on Hela cells, and no significant effect was observed.

  • 出版日期2017-11