Emerging aerosol drug delivery strategies: From bench to clinic

作者：Rubin Bruce K^*; Williams Ronald W

来源：Advanced Drug Delivery Reviews, 2014, 75: 141-148.

DOI：10.1016/j.addr.2014.06.008

• Aerosol therapy
• Nebulizer
• Pressurized metered dose inhaler
• Vibrating mesh nebulizer
• Engineered particle

Patients with tracheostomies, those requiring mechanical ventilation, and those too small or compromised for conventional devices, are realizing the benefits of increasingly sophisticated aerosol delivery systems. New medicines and novel aerosol formulations, have enhanced our ability to treat lung disease, and are opening the doors for therapy to treat diseases like diabetes, pulmonary hypertension, and cancer. Progress in the aerosol delivery of drugs has been spurred by the significant benefits, including ease of use, patient comfort, greater selectivity of effect, and the potential to decrease side effects.

• 出版日期2014-8-20