BALANCE AND COORDINATION TRAINING, BUT NOT ENDURANCE TRAINING, ENHANCES SYNAPTOPHYSIN AND NEUROTROPHIN-3 IMMUNOREACTIVITY IN THE LUMBAR SPINAL CORD AFTER SCIATIC NERVE CRUSH

作者：Bonetti Leandro Vicosa; Ilha Jocemar; Krauthein Schneider Ana Paula; Barbosa Silvia; Faccioni Heuser Maria Cristina^*

来源：Muscle & Nerve, 2016, 53(4): 617-625.

DOI：10.1002/mus.24889

• balance
• coordination
• endurance
• neurotrophin
• synaptophysin

Introduction: Numerous rehabilitation treatments have been shown to be useful for peripheral and central restoration after (PNI). Methods: After sciatic nerve crush, we investigated 4 weeks of endurance training (ET) and balance and coordination training (BCT) with sciatic function index, hind-paw stride length, and spinal cord dorsal horn synaptophysin and neurotrophin-3 immunoreactivity. Results: Our results demonstrated no significant differences between the non-trained (NT), ET, and BCT groups in sciatic functional index, and in stride-length analysis, but the ET showed higher values compared with the NT group. Synaptophysin immunoreactivity was higher in the BCT group compared with the NT group, and neurotrophin-3 immunoreactivity in the BCT group was greater compared with the other groups. Conclusion: BCT can positively affect spinal cord plasticity after a (PNI), and these modifications are important in the rehabilitation process.

• 出版日期2016-4