Nonlinear-optical brain anatomy by harmonic-generation and coherent Raman microscopy on a compact femtosecond laser platform

作者：Doronina Amitonova Lyubov V^*; Lanin Aleksandr A; Ivashkina Olga I; Zots Marina A; Fedotov Andrei B; Anokhin Konstantin V; Zheltikov Aleksei M

来源：Applied Physics Letters, 2011, 99(23): 231109.

DOI：10.1063/1.3664345

An extended-cavity Cr:forsterite laser is integrated with a photonic-crystal fiber soliton frequency shifter and a periodically poled lithium niobate spectrum compressor for simultaneous harmonic-generation and coherent Raman brain imaging. Adapting the laser beam focusing geometry to the tissue morphology is shown to enable complementarity enhancement in tissue imaging by second-and third-harmonic generation, as well as coherent Raman scattering, facilitating quantitative image analysis.

• 出版日期2011-12-5