A new furanosteroid from Talaromyces sp lgt-4, a fungal endophyte isolated from Tripterygium wilfordii

作者:Zhi, Kang-Kang; Yang, Zhong-Duo*; Zhou, Shuang-Yan; Yao, Xiao-Jun*; Li, Shuo; Zhang, Fei
来源:Natural Product Research, 2016, 30(19): 2137-2141.
DOI:10.1080/14786419.2016.1138301

摘要

Wortmannolol (1), a new furanosteroid, along with five known compounds, wortmannolone (2), ergosterol (3), p-hydroxyphenyl ethanol (4), trans-6-dodecene (5), (2Z, 4E) -5-(8-hydroxy-1,5-dimethyl-3-oxo-6-oxabicyclo [3.2.1] octan-8-yl) -3-methylpenta-2,4-dienoic acid (6) were isolated from a fungal endophyte Talaromyces sp. lgt-4. Their structures were elucidated by IR, MS, 1D and 2D NMR spectra. Compound 1 show weak monoamine oxidase inhibitory activity. @@@ [GRAPHICS] @@@ .