HOST RESPONSE A multimodal antiretroviral protein

作者：Bieniasz Paul D^*

来源：Nature Microbiology, 2018, 3(2): 122-123.

DOI：10.1038/s41564-017-0104-4

APOBEC3G is an antiviral protein that has long been known to inhibit retrovirus replication by hypermutating viral DNA. An additional mechanism is now identified, in which APOBEC3G binds to the HIV-1 reverse transcriptase, inhibiting viral DNA synthesis.

• 出版日期2018-2