A flow cytometry-based dopamine transporter binding assay using antagonist-conjugated quantum dots

作者:Kovtun Oleg; Ross Emily J; Tomlinson Ian D; Rosenthal Sandra J*
来源:Chemical Communications, 2012, 48(44): 5428-5430.
DOI:10.1039/c2cc31951a

摘要

Here we present the development and validation of a flow cytometry-based dopamine transporter (DAT) binding assay that uses antagonist-conjugated quantum dots (QDs). We anticipate that our QD-based assay is of immediate value to the high throughput screening of novel DAT modulators.

  • 出版日期2012