Nanocrystalline TiO2-HClO4 catalyzed three-component preparation of derivatives of 1-amidoalkyl-2-naphthol, 1-carbamato-alkyl-2-naphthol, 1-(alpha-aminoalkyl)-2-naphthol, and 12-aryl-8,9,10,12-tetrahydrobenzo[a]-xanthen-11-one

作者：Shaterian Hamid Reza^*; Mohammadnia Majid

来源：Research on Chemical Intermediates, 2013, 39(9): 4221-4237.

DOI：10.1007/s11164-012-0938-6

• Nanocrystalline
• TiO2-HClO4
• Reusable catalyst
• Three-component reactions

1-Amidoalkyl-2-naphthols, 1-carbamatoalkyl-2-naphthols, and 1-(alpha-aminoalkyl)-2-naphthols have been prepared by three-component reaction of 2-naphthol, aromatic aldehydes, and NH compounds, i.e. amides, carbamates, and secondary amines, respectively, in the presence of a catalytic amount of nanocrystalline TiO2-HClO4. In addition, 12-aryl-8,9,10,12-tetrahydrobenzo[a]-xanthen-11-one derivatives have been synthesized by reaction of 2-naphthol, aromatic aldehydes, and dimedone in the presence of the same nano catalyst. These reactions were studied under solvent-free conditions. This white acidic heterogeneous catalyst is very stable under the reaction conditions and was reused several times without significant loss of activity.

• 出版日期2013-11