Studies on synthesis, structure, and DNA cleaving of homo-dinuclear Mn(II), Cu(II), Ni(II), and Zn(II) complexes with a heterocycle-based macroacyclic Schiff base

作者：Baran Talat; Karaoglu Kaan; Serbest Kerim^*; Agir Hulya; Sandalli Cemal; Degirmencioglu Ismail

来源：Monatshefte fur Chemie, 2013, 144(8): 1107-1115.

DOI：10.1007/s00706-013-0926-6

• Coordination chemistry
• Heterocycles
• Schiff bases
• Binucleating
• DNA cleaving

(E,E',E'',E''')-N,N',N'',N'''-[(1,2-ethenyliden)tetrakis[methylenoxy(2,1-naphthalinediyl)methylidyne]tetrakis[1,2,4-triazol-4-amine] and its novel homo-dinuclear Mn(II), Ni(II), Cu(II), and Zn(II) complexes have been synthesized and characterized by elemental analyses, spectroscopic data (i.e., IR, H-1 and C-13 NMR, UV-Vis), electrospray ionisation mass spectra, XRD, DSC, molar conductivity, and magnetic susceptibility measurements. The absorption bands observed in the electronic spectra and magnetic moment values confirm an octahedral environment around the metal ion. The molar conductivity measurements confirm the non-ionic character of these complexes. The DNA cleavage activities of the Schiff base and its homo-dinuclear complexes are also investigated. Results suggest that all the complexes used can be evaluated as nuclease mimics.

• 出版日期2013-8