Directed self-assembly of polypeptide-engineered physical microgels for building porous cell-laden hydrogels

作者:Yao, Ming-Hao; Yang, Jie; Song, Ji-Tao; Zhao, Dong-Hui; Du, Ming-Shuo; Zhao, Yuan-Di*; Liu, Bo
来源:Chemical communications, 2014, 50(66): 9405-9408.
DOI:10.1039/c4cc04018j

摘要

A novel approach to build porous cell-laden hydrogels through the self-assembly of coiled-coil polypeptides on the surface of physical microgels was developed. Both the extracellular microenvironments of pores and physical microgels within assembled constructs could be tailored simultaneously by tuning the polypeptide and morphological features of microgels.