A Critical Aooraisal of Control Stratecies for Soil-Transmitted Helminths

作者：Campbell Suzy J; Nery Susana V; McCarthy James S; Gray Darren J; Magalhaes Ricardo J Soares; Clements Archie C A

来源：Trends in Parasitology, 2016, 32(2): 97-107.

DOI：10.1016/j.pt.2015.10.006

Interventions that lead to reductions in soil-transmitted helminths (STHs) include chemotherapy with anthelmintic drugs and improvements in water, sanitation, and hygiene (WASH). In this opinion article we aim to determine the evidence for optimal approaches for STH control. First we explore the evidence for the above interventions. We then appraise two integration strategies: current chemotherapy-oriented integrated neglected tropical disease. (NTD) control and expanded `multicomponent integration', which includes integrated chemotherapy, WASH, and other intervention strategies. While multicomponent integrated control may be an effective approach to sustainably reduce STH transmission, there is a need for evidence to prove the feasibility of this approach.

• 出版日期2016-2