Mechanisms of macrolide resistance among Streptococcus pneumoniae isolates from Russia

作者：Reinert Ralf R; Filimonova Olga Y; Al Lahham Adnan; Grudinina Svetlana A; Ilina Elena N; Weigel Linda M; Sidorenko Sergey V^*

来源：Antimicrobial Agents and Chemotherapy, 2008, 52(6): 2260-2262.

DOI：10.1128/AAC.01270-07

Among 76 macrolide-nonsusceptible Streptococcus pneumoniae isolates collected between 2003 and 2005 from Central Russia, the resistance mechanisms detected in the isolates included erm(B) alone (50%), mef alone [mef(E), mef(I), or a different mef subclass; 19.7%], or both erm(B) and mef(E) (30.3%). Isolates with dual resistance genes [erm(B) and mef(E)] belonged to clonal complex CC81 or CC271.

• 出版日期2008-6
• 单位河北医科大学