Four new glucosides from the aerial parts of Mediasia macrophylla

作者：Kurimoto Shin ichiro; Okasaka Mamoru; Kashiwada Yoshiki^*; Kodzhimatov Olimjon K; Takaishi Yoshihisa

来源：Journal of Natural Medicines, 2011, 65(1): 180-185.

DOI：10.1007/s11418-010-0444-3

• Mediasia macrophylla
• Glucosides
• Umbelliferae
• Uzbekistan

As part of our chemical studies on the medical plants in Uzbekistan aimed at searching for new drug leads, we have examined the aerial parts of Mediasia macrophylla. This has resulted in the isolation of four new glucosides, together with 30 known compounds. The structures of new compounds were elucidated as (1'S)-(4-hydroxyphenyl) ethane-1',2'-diol 2'-O-beta-glucopyranoside (1), 3-(4'-methoxyphenyl)-propanol 1-O-beta-glucopyranoside (2), 2-methoxy-3-hydroxy-5-(E)-propenyl-phenol 1-O-beta-glucopyranoside (3), 1-O-angeloyl-beta-glucopyranose (4), on the basis of spectral analysis.

• 出版日期2011-1