Autophagy-Mediated Tumor Promotion

作者:Guo Jessie Yanxiang; Xia Bing; White Eileen*
来源:Cell, 2013, 155(6): 1216-1219.
DOI:10.1016/j.cell.2013.11.019

摘要

Mouse models for cancer are revealing novel cancer-promoting roles for autophagy. Autophagy promotes tumor growth by suppressing the p53 response, maintaining mitochondrial function, sustaining metabolic homeostasis and survival in stress, and preventing diversion of tumor progression to benign oncocytomas.

  • 出版日期2013-12-5
  • 单位rutgers