Addition-type Oxidation of Silylalkene Using Ozone: An Efficient Approach for Acyloin and Its Derivatives

作者:Igawa Kazunobu; Kawasaki Yuuya; Tomooka Katsuhiko*
来源:Chemistry Letters, 2011, 40(3): 233-235.
DOI:10.1246/cl.2011.233

摘要

Acyloins are efficiently synthesized in three steps from alkynes via hydrosilylation followed by an addition-type ozone oxidation and hydrogenation. The key intermediate alpha-silylper-oxy ketone is convertible to not only acyloin but also O-silylated acyloin and diketone.

  • 出版日期2011-3-5